The National Cancer Institute has awarded Yale University a five-year, $11 million grant to establish a new research program to study the biology and personalized treatment of lung cancer. The so-called Specialized Program of Research Excellence, or SPORE, initiative is specifically focused on developing novel therapeutics and personalized prevention strategies by improving the understanding of targetable biochemical and immunological pathways involved in the progression of lung cancer and the acquisition of resistance to therapy, according to the grant’s abstract. [Read more…]
Second cancers are on the rise. Nearly 1 in 5 new cases in the U.S. now involves someone who has had the disease before. When doctors talk about second cancers, they mean a different tissue type or a different site, not a recurrence or spread of the original tumor.
Judith Bernstein of suburban Philadelphia is an extreme example. She has had eight types over the last two decades, all treated successfully. “There was a while when I was getting one cancer diagnosis after another,” including breast, lung, esophageal, and the latest — a rare tumor of her eyelids, she said. “At one point I thought I had cancer in my little finger.” [Read more…]
Enhanced oral cancer detection can help general practitioners save patients’ lives while protecting dentists from malpractice lawsuits, according to a presentation by Dr. Jonathan Bregman at this week’s California Dental Association’s CDA Presents 2015 meeting.
The early detection of oral cancer, which has been aided by new high-tech screening devices, was the focus of Dr. Bregman’s session. He stressed the importance of creating an effective protocol that practices should use, including assessing risk factors and being aware of the changing demographics of the disease. [Read more…]
When he was surgeon general of the U.S., David Satcher, MD, PhD, issued the first surgeon general’s report on oral health in 2000. He has continued to show that oral health matters, as he is now championing the use of dental therapists as a way to reduce the prevalence of caries and provide oral healthcare to underserved populations.
In this exclusive interview with DrBicuspid.com, Dr. Satcher talks about the need to improve the oral health of all Americans, how the first surgeon general’s report on oral health came into being, the need for more outcomes research in dentistry, and why it’s not about dentists versus dental therapists. [Read more…]
Pain is the first and most significant symptom of oral cancer, with patients experiencing serious pain even if their tumors are quite small. In response to this, researcher Shivani Ruparel from the UT Health Science Center San Antonio was awarded a $144,000 grant from the American Cancer Society to assess the phenomenon of oral cancer pain. This grant is one of 100 dedicated to national research and training that represent over $45.6 million invested by the ACS this year alone. [Read more…]
It is easy to get wrapped up in the day-to-day routine of doing a crown, filling a cavity, and hopping from one hygiene exam to the next. Our time is important and we have a schedule to maintain, right? While all this is important, the role that we have as health-care providers goes way beyond just fixing teeth — we have a responsibility in the medical community to detect and treat oral cancer. [Read more…]
Rob Abrams did. His wife, Caitlin, couldn’t have been happier. She liked it so much she gave Rob the same thing for Christmas. “It was,” Caitlin says, “the most nerdy gift I have ever given and received.”
The package — a small tube, removable cap, and sealable spit funnel — was a genetic testing kit from California company 23andMe. The Abramses spent $299 on each kit in 2011. Once the couple mailed in their tubes, 23andMe tested their saliva for hundreds of genetic markers. The markers pointed toward clinically useless but nevertheless interesting ancestral information (look, Caitlin had 2.9 percent Neanderthal DNA!). They also pointed toward dozens of potential health risks. [Read more…]
If you are lucky, you’re on your way to a diagnosis and a path to feeling better. How much more personal does it get? In fact, much more. In theory, astonishingly more.
Most often today, your treatment plan doesn’t have all that much to do with you specifically. It’s identical to what doctors would hand over to essentially anyone with the same condition — your neighbor, the hot dog vendor at Wrigley Field, or the prime minister of Bangladesh. [Read more…]
Almost half of the deaths caused by cancers of the oral cavity and pharynx in U.S. adults 35 and older in 2011 were attributable to cigarette smoking, according to a multi-institution research letter published in JAMA Internal Medicine.
Overall, almost 346,000 people died of one of 11 cancers in 2011 in the U.S. (see list below), including about 150,000 women and more than 197,000 men. Of these deaths, 48.5% were attributable to cigarette smoking. [Read more…]
In 2013, the Canadian Cancer Society estimated that there were 4100 new cases of oral cancer diagnosed. Eleven new cases each day! On average, 16 years of life is lost to oral cancer, one more than all cancers in general. American statistics show that there are three times as many deaths from oral cancer as there is from cervical cancer. [Read more…]