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New York State has a separate and unique regulatory approval process for laboratory diagnostic testing. PeriRx is currently in the application process with our SaliMark™ OSCC test and is vigorously committed to pursuing this application approval. 

How to Administer a Test

The use of SaliMark™ OSCC for oral cancer will help to quantify the risk of cancer in patients with lesions detected on oral screening exams. The SaliMark™ OSCC test is painless, takes only a few minutes to administer and is easy to incorporate into the workflow of any practice. The patient should not eat, drink, smoke, chew gum, brush or floss for at least an hour before the test is administered. This entire salivary collection process should just take you a few minutes.

Here’s how the SaliMark™ OSCC test is administered:

1Step 1

Your patient must wait an hour after eating or smoking to take the test. Perform a thorough oral cancer exam by visual inspection and palpation.


2Step 2

If you identify a suspicious lesion or abnormality, discuss it calmly with your patient and explain the role of the SaliMark™ OSCC test in quantifying their level of risk.

Step 3

All of the supplies necessary for the administration of SaliMark™ OSCC are contained in the Test Kit.

  • Collection Funnel and Tube
  • Tube Cap
  • Identification Label
  • Bio-hazard Bag
  • Prepaid FedEx Label
  • Bubble Envelope

4Step 4

Have the patient thoroughly rinse their mouth with water and collect 2 cc of saliva (not sputum) in the specialized collection tube by using the detachable funnel.


5Step 5

After collecting the saliva, replace the funnel with the cap provided, and shake the vial for approximately 30 seconds to activate the preservative.


6Step 6

Identify the sample with the patient’s name and birthday.


7Step 7

Register the patient in your practice account by name, and birthday. A unique ID number will be automatically generated on a bar coded requisition.


8Step 8

Seal the saliva specimen in the biohazard bag before placing the sample in the bubble envelope. Fold up and include the completed patient bar coded requisition in the shipping envelope. Ship via FedEx to the laboratory for analysis using the provided label.


9Step 9

Log into the HIPAA secure website to review results within 72 hours.


10Step 10

Arrange for appropriate follow up to discuss the potential next steps outlined below.


Step 11

For high risk test, refer for consideration of biopsy; for moderate risk test, obtain a second opinion from a specialist and the decision for biopsy will depend on the test score and other clinical features; for low-risk test, schedule follow up to ensure resolution.